High shear coating is a process in which powdered lipid excipient is mixed with the API in a high shear coater, without external heating. During mixing, frictions are generated. They are responsible for the production of heat and consequently of the partial melting of the lipid excipient. The partially molten lipid excipient coats the drug particles. Upon cooling the lipid coating solidifies and efficiently covers the drug particle, masking its taste.
Range of excipients for high shear coating