Geloil™ SC

A thixotropic suspension vehicle for pharmaceutical APIs. Ready-to-use in a cold process for thermosensitive actives in soft gel capsule.

Names and synonyms

USP NF Name

Mixture of refined soybean oil USP-NF, glyceryl distearate USP-NF and polyglyceryl-3 dioleate USP-NF

EP Name

Mixture of refined soybean oil EP, glyceryl distearate EP and polyglyceryl-3 dioleate

UNII Code (FDA)

241ATL177A 73071MW2KM XRQ165498B

Preferred Substance Name (FDA)

Soybean oil Glyceryl distearate Polyglyceryl-3 oleate

Handbook of Pharmaceutical Excipients

Soybean oil Glyceryl palmitostearate

Food status

Soybean oil: food grade Glyceryl palmitostearate: FCC, GRAS 21 CFR §184.1329, JSFA Polyglyceryl-3 dioleate: E475, FCC, GRAS 21 CFR§172.854, JSFA

Chemical description

Consists of a mixture of refined soybean oil, glyceryl distearate (C18) and polyglyceryl-3 dioleate (C18:1)

Key characteristics

Product form

Viscous gel

HLB

5

Main functionalities

Vehicle to suspend pharmaceutical ingredients in soft gelatin capsule.
Good dispersibility in aqueous fluid.
High drug load achievable.
Thixotropic behavior: can be processed only by mixing—ideal for sensitive actives.
Safety of use is inferred by food additive status and precedence of use.

Main formulation technologies

Soft capsule filling