An oily vehicle and solubilizer for lipophilic APIs in topical dosage forms. Widely used as a vehicle in veterinary parenteral formulations.
Names & synonyms
|USP NF Name||
Propylene glycol dicaprolate/dicaprate
Propylene glycol dicaprylocaprate
|UNII Code (FDA)||
|Preferred Substance Name (FDA)||
PROPYLENE GLYCOL DICAPRYLATE/DICAPRATE
|Handbook of Pharmaceutical Excipients||
Consists of propylene glycol esters of caprylic (C8) and capric (C10) acids
Oily phase for topical formulations. Oily vehicle and solubilizer for solutions. Safety of use is inferred by substantial toxicological data and precedence of use in approved human and veterinary pharmaceutical products.