A nonionic oil-in-water emulsifier for topical emulsions. It provides excellent emulsion stability with difficult-to-formulate and combination APIs. Provides heat stability and high tolerance over a wide pH range.
Consists of a mixture of glycerol monostearate and PEG-75 (MW 3500) stearate (C18)
Key characteristics
Product form
Pellets
Melting range
55.5 – 62.5
HLB
10
Main functionalities
Emulsifier for difficult-to-formulate APIs, API combinations, anhydrous emulsion. Associate with Emulcire™ 61 WL2659 to enhance sensorial and texture properties. Safety of use is inferred by precedence of use in approved pharmaceutical products.
Softer Skin Stick (2613-1.17) is a 99% natural origin scrub in the practical form of a stick. It is possible to use it on dry skin or on wet skin for a more slippery application. Its texture, stabilized with Emulium® Dolcea MB, emulsify on contact with water, for an easy rinsing.
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Everything Balm (2620-1.02) is a 99% natural origin anhydrous multifunctional balm that takes care of the skin of the face, the body, the hands and also the lips and the hair. It contains Acticire® MB which allows the incorporation of aqueous ingredients such as active ingredients or colorants, for more customization!
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Magma Mask (2618-2.52) is a 98% natural origin mask in the form of surprising solid black pellets, obtained thanks to Geleol™ MB and Emulium® Kappa MB. One pellet represents a unique dose of a product, making it possible to take only the needed quantity. First, crush a pellet of the Magma Mask in your palm, then take a bit of 2620-1.02 Everything Balm (or alternatively hot water). Mix to form a thick black mask to spread directly onto the skin and rinse after 10 minutes.
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Scalp & Body Scrub (2628-1.07) is a 94% natural origin anhydrous wax with grains of sodium bicarbonate that gently exfoliates and cleanses the scalp, then rinses easily as grains will be dissolved by water, leaving no particles in the hair. The presence of Emulium® Kappa MB helps to improves rinsing while Acticire® MB boosts foam formation. It can also be used on the body for a 2-in-1 application.
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Slide n’ Foam (2621-2.09) is a 92% natural origin solid face cleanser that invites to a new gesture! Apply the product directly onto dry skin, then rub the skin with wet hands to create foam, boosted by Acticire® MB, and clean the skin. Thus, the product is not damaged by water and is gentler for the skin. Indeed, only the right amount is applied thanks to its melting texture obtained with the help of Lipocire™ A SG.
A non-ionic pure surfactant for lipid-based formulation to solubilize and increase oral bioavailability of poorly soluble API. Forms micellar solution in aqueous media.
\n","names_kv":[{"keys":"USP NF Name","value":"
Polyoxyl-32 stearate (type I) NF
\n"},{"keys":"EP Name","value":"
Macrogol-32 stearate (type I) EP
\n"},{"keys":"UNII Code (FDA)","value":"
33GX5WQC0M
\n"},{"keys":"Preferred Substance Name (FDA)","value":"
PEG-32 STEARATE
\n"},{"keys":"Handbook of Pharmaceutical Excipients","value":"
Polyoxylethylene stearates
\n"},{"keys":"Chemical description","value":"
Consists of PEG-32 (MW 1500) esters of palmitic (C16) and stearic (C18) acids
Solubilizer for low log P APIs and bioavailability enhancer. Single excipient formulation system: self-emulsifies in aqueous fluid into micellar solution—LFCS Type IV. Use in melt processes (granulation, extrusion), granulation, and compression. Wetting agent. Safety of use is inferred by precedence of use in approved pharmaceutical products.
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Sensorial experts for more than 20 years, Gattefossé consistently surprises and delights with innovative cosmetic textures.
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Five years ago, Gattefossé created INSPIRATION; a tool to discover new sensorial experiences and galvanize creativity. This creative concept provides pleasure, a sense of astonishment, and motivation to awaken formulators’ innermost imaginations.
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INSPIRATION highlights one or more topics, each of which offers a refreshing take through novel textures and visuals. The prototypes that illustrate each idea will encourage formulators to rediscover Gattefossé’s ingredients outside of their comfort zone.
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INSPIRATION for 2023 presents a new topic: DARING ON THE DAILY
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This year, Gattefossé invites customers to re-enchant their daily lives and dare to be unique. Due to a world in constant flux, consumers are reinventing their routines, rather than following normal conventions.
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For this new INSPIRATION, Gattefossé sets the tone for 2023 by giving a new narrative called: DARING ON THE DAILY! It is a joyful invitation that shakes up everyday conventions to celebrate life as a manifesto and assert your uniqueness.
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This new expression of beauty is highlighted by 3 main themes – I.D. Manifesto, Playground, and Experience the Unexpected – encouraging disruptive & playful cosmetics.
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Inspired by these trends, Gattefossé’s application lab has developed a collection of 7 innovative formulas that break the norms and explore new territories. Surprising & delightful, this new collection invites everyone to have fun, be bold, and be whimsical!
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Be “daring on the daily”!
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7 new formulas to shake up your daily routine and dare you to be yourself!
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I.D. Manifesto
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It is no longer a question of trying to hide imperfections; but letting them be a pathway to individuality. This trend anchors a desire for self-acceptance and self-expression.
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Primer-to-Powder (2479-2.04) is a makeup base featuring Emulium® Illustro. It starts with a rich, creamy texture that dries down to a powdery, matte finish, and leaves a silky smooth, even skin tone with long-lasting comfort and moisturization. \n (99.6% natural origin)
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Let’s now discover the Glittering Gummies (2745-3.04), a surprising travel-friendly format for a highlighter, made possible by Emulium® Kappa MB! Compact and easy to carry, this solid O/W emulsion is perfect for touch-ups on the go.
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It offers an ultra-bouncy effect and melting sensation thanks to Lipocire® A SG and creates a fresh and watery effect upon application. \n (97.4% natural origin)
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Craving uniqueness? The Holo Eye Liner (2758-1.11) has been designed to reveal the eccentricity living in you while reamining smudge-free and waterproof. Creamy and quick-drying, it melts seamlessly thanks to Lipocire® A SG to leave an intense purple, holographic line with long-wear properties! Emulium® Dolcea MB shows unfailing efficiency and robustness with this formula rich in pigments. \n (92% natural origin)
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Playground
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What if everyday life became a playground (again)? Gattefossé encourages more playful cosmetic application with our Cottage Cheese cream (2748-1.11) and its Squid Ink Topping (2748-2.04)! With Emulium® Dolcea MB, Acticire® MB, and EnergiNius® this creamy, yogurt-like texture delivers moisturizing and energizing benefits, perfect for daily application. Recommended once a week or once a month, mix it with 2 drops of the Squid Ink Topping, enriched with Original Extract® Ginger, to create your own detox mask! \n (99.5% natural origin)
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Experience the unexpected
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It’s time to discover new territories! Between the real and imaginary, appearances can be misleading… \n Like the Chayote-Kiwi Sorbet (2694-3.03), is it a beauty sorbet or a granita? With its light green color, you first see a food-like texture that you would love to eat. Upon initial application, you’ll feel a fresh, creamy yet powdery sensation, that leaves a dry, soft, non-tacky after-feel due to Emulium® Mellifera MB. This cushion cream brings a refreshing and intense moisturization, acts as a blur, and protects the skin from photoaging with Solastemis™. The skin appears radiant, even, and healthy. \n (99.4% natural origin)
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Alien Slime (2614-3.01) is another optical illusion! is it slime, or is it a cosmetic? Try it and you’ll be surprised by its comfortable, stringy, but non-sticky after-feel thanks to Emulium® Dolcea MB & Acticire® MB.
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Adapted for sensitive skin, it has a long playtime which is perfect for a soothing massage! It can also be used as a leave-on so that you can appreciate its nourishing properties. \n (98.2% natural origin)
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Bi-gels consist of an intimate mixture of an aqueous gel and an oily gel.
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Due to their dual nature, bi-gels are associated with the following advantages:
Improves the texture and enables a smooth and easy application on the body
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Numerous studies have shown that poor texture and sensorial properties negatively impact patient experience and adherence to treatment. The good news is there is plenty of scope for innovation and improvement in topical dosage forms if the patient’s experience of texture and sensorial properties is taken into consideration during formulation development. \r\n \r\nSensory analysis is a scientific discipline that applies the principles of experimental design and statistical analysis to measure, analyze, and interpret the characteristics of a product as they are perceived by the senses. \r\n \r\nGattefossé has developed validated methods and established an in-house sensorial analysis panel. Using this approach, we can evaluate the sensorial properties of our prototype formulations to \r\n•\tevaluate the influence of new raw materials in formulation, \r\n•\tevaluate the main texture characteristics of our emulsifiers, \r\n•\tcompare prototypes with market references, \r\n•\tunderstand market preferences, \r\n•\tconstruct a broad texture database. \r\n","":false,"content":[{"wysiwyg":"
A trained panel and validated methods for reliable results
\n
\n
Our sensory panel brings together over a dozen trained staff members, both men and women. They test new formulations approximately twice a week. The assessments are carried out using specific protocols and standardized procedures, and the results are statistically analyzed.
\n
Tests cover vision and touch, and they evaluate the following criteria:
\n
\n\n
\n
Initial touch \n
\n
pick-up
\n
texture
\n
creaminess
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\n
\n
\n
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During application\n
\n
spreadability
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tackiness
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play time
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greasiness
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softness
\n
absorption
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\n
\n
After absorption\n
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residual film
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tackiness
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greasy after-feel
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soft after-feel
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shine
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\n\n
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The power of sensorial mapping
\n
\n
\n
\n
This sensorial map shows the results with cream formulations formulated with different Gattefossé pharmaceutical-grade emulsifiers. It enables direct and visual comparison and can help to select the emulsifier or appropriate prototype formulation.
\n
Click on the image to enlarge.
\n
\n
For more information on how to develop formulas for optimized texture and sensory properties, please see our topical formulation section.
Incorporated in France as a “Société par actions simplifiée” with a capital of 4,650,000 euros, registered with the Lyon Trade and Companies Register under No. 389 586 900,
\n
Publishing Director: Ségolène Moyrand-Gros, Group Director – Corporate Development
\n
Hosted by:
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\n GATTEFOSSE SAS
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While requirements for sustainably driven product development have never been so real, the importance of natural actives as a key part of cosmetic formulations increases greatly.
\n
Consumer expects powerful efficacy from natural products. The challenge therefore is to find extraction methods that are both natural and effective in extracting the key active molecules from plants.
\n
When extracting active metabolites from botanicals, some molecules are more challenging than others. Despite perfect solubility in plant tissues, many of these molecules are poorly soluble in water or lipids, and even in the most efficient known solvents. Additionally, traditional solvents such as butylene glycol or alcohol are no longer acceptable to many consumers.
\n
Since 2012, Gattefossé scientists’ teams have been working on the design of a new generation of 100% natural solvents to create highly functional active ingredients: they are called Natural Deep Eutectic solvents or NaDES.
\n
\n
\n
A nature-inspired solution
\n
This new category of green solvents is directly inspired by botanicals and the way in which metabolites are solubilized inside the plant – through eutectic combinations of simple chemicals such as sugars, nitrogen compounds, and organic acids. \n Working with researchers from Leiden University, Gattefossé has developed and patented several natural eutectic solvents, perfectly adapted for the extraction of cosmetic active ingredients (1). This exciting class of solvents uses all-natural components such as sugars, polyols, amino acids.
\n
\n
But what does NaDES mean?
\n
\n
A NaDES can be defined as a eutectic mixture formed by a combination of natural compounds with specific molar ratio. It melts at a single, sharp unique temperature named the “eutectic point” (the lowest melting point for a specific composition) and is characterized by a supramolecular structure.
\n
This homogenous liquid is stable once the eutectic point is reached, making possible its use for extraction applications.
\n
\n
NaDES by Gattefossé
\n
\n
Through an ambitious research program, Gattefossé revealed many advantages linked to this extraction technology.
\n
\n
Completely natural, NaDES combinations benefits from a perfect affinity with plants enabling to reach high extraction potential. The botanical extracts obtained unveil unique phytochemical signature, and performance that would be impossible to reach using conventional solvents. \n Gattefossé thus makes the most of this technology to rediscover well known plants in cosmetics (Calendula, Mallow, Rose, Horse Chesnut…), and opens therefore new fields of possibility. \n 2 applications patents have already been granted (2).
\n
\n
Bright perspectives
\n
\n From plants and solvents selection to industrialization stage, we master in house all the steps of the development and manufacturing process. \n Our research teams are committed to continue exploring the potential of NaDES. \n Our research perspectives are still wide, and the coming years will surely see the rise of new NaDES active ingredients. \n Natural, non-toxic and efficient at low temperatures, the NaDES technology is perfectly aligned with Gattefossé commitments to provide high-performance sustainable active ingredients.
\n\n
Want to know more about the NaDES technology? Do not hesitate to contact your local sales representative.
\n
\n (1) Patent FR3036618B1, GATTEFOSSE SAS, CAPRIN B, CHARTON V, DEMARNE F: Vegetable extracts for cosmetics, solvents and methods for obtaining same \n (2) Patent FR3053890B1, US10363212B2, GATTEFOSSE SAS, CHARTON V, CAPRIN B, BECHETOILE N: Aesculus Hippocastanum extract \n (2) Patent FR3067939A1, GATTEFOSSE SAS, BECHETOILE N, LOPIS-PRESLE S: Extract of Whitania Somnifera to fight against the harmful effects of visible light on skin
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Highest-purity solvent and solubilizer for solubility and bioavailability enhancement for oral and alternative routes.
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Diethylene glycol monoethyl ether
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Diethylene glycol monoethyl ether
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DIETHYLENE GLYCOL MONOETHYL ETHER
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Diethylene glycol monoethyl ether
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The North American region is a leading market for pharmaceuticals and personal care with important local production, consumption and a major influence on global trends. Within this favorable context, Gattefossé North America has enjoyed continuous growth in its business activity since its creation in 1982.
\n
To expand its presence in the region, the Gattefossé Group has decided to establish its fourth Technical Center of Excellence in Paramus, New Jersey. Mr. Jacques Moyrand, Gattefossé Group Chairman, Mr. Olivier Midler, Gattefossé Group CEO and Mr. Eric Brun, President and CEO of Gattefossé USA and Canada, will inaugurate the North America Technical Center of Excellence on Wednesday, April 26th 2017. This center brings together pharmaceutical and personal care application laboratories in a 5,300 ft² (492 m²) space with state-of-the-art equipments.
\n
The technical team will offer an essential interface with both pharmaceutical and personal care customers throughout North America by providing formulation troubleshooting, inspiration and technical support.
\n
For pharmaceuticals, high priority will be given to oral bioavailability enhancement and modified release applications. For personal care, the laboratory will develop specific formulas to answer local needs and to capture local trends.“The latest sign of our investment in this strategic market is the creation of the Gattefossé North America Technical Center of Excellence. These state-of-the-art application laboratories located in Paramus, New Jersey, will ensure our customers responsive service adapted to their market”.
\n
Eric Brun, President and CEO of Gattefossé USA and Canada
\n
\n
About Gattefossé North America
\n
\n\n
The USA and Canadian affiliates of Gattefossé (created respectively in 1982 and 1997) were established to provide local service and support to the.pharmaceutical and personal care industries in North America. Since its creation, Gattefossé North America has enjoyed continuous growth, expanding its presence as a provider of innovative solutions involving performance ingredients.
\n
Under the leadership of Eric Brun, Ph. D, a specialized team of professionals, including marketing, customer service, supply chain, quality, and technical support, is fully committed to servicing customers from the corporate offices in Paramus, NJ, Toronto, ON and Montreal, QC. Local service is also provided by long-term partners in the US Midwest and West Coast, as well as Mexico.
\n
Today, Gattefossé has 34 employees and 3 offices in North America as well as 3 warehouses in Edison (NJ), La Mirada (CA) and Toronto (Canada).
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We all know that naturalness is no longer just a trend, it is a prerequisite for any new cosmetic product launch. Indeed, it is one of the main consumer expectations, not only in Europe but also throughout the world.
\n
\n
Formulation of natural cosmetics is not so easy
\n
\n
Formulating a natural cosmetic product is not that simple, for various reasons:
\n
\n
The naturality of the cosmetic ingredients is not always clearly indicated, and the calculation methods used vary from one supplier to another (ISO 16128, COSMOS…)
\n
The formula stability is an essential point to check before launching a new product
\n
The formula must be perfectly tolerated by all skin types
\n
Textures must be always more innovative to attract consumers’ attention
\n
Sensoriality is a key factor that drives purchase intention
\n
\n
Formulating a natural cosmetic product therefore takes longer, whereas development times decrease year after year.
\n
\n
The wax butter technology is the solution
\n
\n
This technology leads to the creation of 100% natural origin emulsifiers and texture ingredients which bring moisturizing benefits due to the vegetable waxes and true sensory identities.
\n
It maximizes the advantages of vegetable waxes while overcoming their disadvantages:
\n
\n
\n
\n
A patented technology
\n
\n\n
For over 30 years, Gattefossé has developed a strong expertise in the transformation and functionalization of natural waxes according to the rules of green chemistry. This environment-friendly chemistry enables the creation of new texture ingredients with particularly interesting properties. Gattefossé holds a number of patents on this technology, the most recent of which describe the reaction of solid and liquid waxes in presence of vegetable polyglycerol1. The subject of several scientific papers, communications and recognized as an innovation in textures, this chemistry has been used to create a wide range of texture ingredients.
\n
\n
\n
How does it work?
\n
\n\n
Natural waxes contain fatty acids, fatty alcohols and esters with reactive groups. Adding polyglycerol-3 enables the creation of new sensorial esters though a succession of transesterifications.
\n
\n\n
1) Transesterification between polyglycerol-3 and ester of solid wax:
\n
\n
\n
\n
2) Transesterification between polyglycerol-3 monoester and jojoba wax ester:
\n
\n
\n
\n
3) Transesterification between fatty alcohol of solid wax and polyglycerol-3 diester:
\n
\n
\n
\n
4) Transesterification between polyglycerol-3 monoester and fatty alcohol of jojoba wax:
\n
\n
\n
\n
Summary of all the reactions:
\n
\n
\n
\n
These transesterifications create new jojoba esters that combine the rigidity of the saturated carbon chain with the flexibility of the unsaturated one.
\n
These mixed esters show intermediate physico-chemical properties between solid and liquid waxes. Transforming the waxes improves their behavior and functionality. These new properties include a better solubilization in the lipid phase, amphiphilic behavior, good moisturizing properties and enhanced sensory attributes.
\n
\n
\n
\n
Water absorption capacity
\n
\n\n
The reactions described above create a homogeneous soft wax butter. It has the ability to absorb up to 4 times its weight in water and is central to the moisturizing properties of the ingredients created with this technology.
\n
\n
\n
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Our products range based on the wax butter technology
\n
\n
By varying the types of waxes used, Gattefossé has developed a wide range of emulsifiers and texturizing ingredients with very distinct functional and sensory properties.
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\n
\n
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1 EP1933806, GATTEFOSSÉ SAS, Support comprising a wax derivative for making topical cosmetic formulations, filed on 10 September 2006
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A radiant complexion is an essential characteristic of beautiful skin. Complexion indeed plays a key role in perceptions of youth and beauty around the globe. Gatuline® Radiance enhances microcirculation, bringing blood flow to the surface layers of the skin. This in turn enhances all aspects of a radiant complexion, including skin color and luminosity. Skin brightness is visibly enhanced even under heavy pollution.
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Gatuline® Radiance is obtained from Evodia rutaecarpa, also known as “Wu-Zhu-Yu”, a flowering shrub member of the Rutaceae family. Evodia rutaecarpa is widely cultivated in southeast China for Traditional Chinese Medicine. In addition to its medicinal uses, the Chinese would traditionally wear Evodia on the ninth day of the ninth Chinese lunar month (Double Ninth Festival). The plant was thought to bring luck. Preservative free.
Anti-pollution (the skin is less reactive, durably soothed)
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Alphabet creams
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Skin perfectors
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Illuminating products
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Global antiaging lines
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Lip products (reveals natural rosy color of lips)
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New strategic step for the Group
\n
This new production site will enable the Group to respond to several strategic challenges: \n • Deepen its presence in North America to better meet local customers’ needs, \n • Increase its global production capacity, \n • Provide back-up solutions on 3 continents and bring more supply flexibility to all \n customers. \n Construction will begin in 2021 and the plant should deliver its first customers in 2024.
\n
United States: a key choice for the Group development
\n
“North America is a leading region for the global pharmaceutical and personal care industries in terms of innovation, production and consumption, and has therefore a major impact on worldwide trends. The opening of a manufacturing unit represents an essential milestone in our strategy to enhance our local presence and commitment to this important and influential market. The label “Made in USA” will satisfy a strong demand expressed by our customers and the geographical location of this new site will facilitate logistics and supply chain. Production in Texas is first intended to serve the North American market but will gradually be extended to other regions” says Eric Brun, President and CEO of Gattefossé USA and Canada.
\n
Today, the Gattefossé Group operates 2 production sites, in Europe (France) and Asia (Singapore).
\n
The opening of a third manufacturing plant in the United States will improve the Group’s ability to better serve the American market and represents an extra step in the deployment of its industrial operations. The company chose to set up a plant in Lufkin, Texas, because of its central position in North America, close to the important industrial pole in Houston. Lufkin is a dynamic up and coming city of 35,000 inhabitants located in the heart of a free trade zone.
\n
A project in line with the Group’s social responsibility
\n
“The international expansion of industrial operations is an essential step in the development of our Group. This project meets the economic and environmental challenges set by the company as part of its global strategy: innovation, customer intimacy, geographic expansion and social responsibility. Controlling our environmental impact is a priority: Gattefossé headquarters will be ISO 14001 certified in 2021 and the new American site will also meet this requirement” explains Eduardo De Purgly, Gattefossé Group CEO.
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Strongly reinforced, the skin is visibly revived in favor of a healthy glow."},"categories":[6],"tags":[],"acf":{"content_not_translated":false,"equivalent_fr":false,"equivalent_en":false,"component":"PageCosmeticProduct","":false,"product_codes":[{"code":"5911"}],"bandeau_image":{"id":13742,"alt":"","title":"EnergiNius","caption":"","description":"","mime_type":"image/jpeg","url":"https://www.gattefosse.com/wordpress/wp-content/uploads/2018/04/EnergiNius.jpg","width":1144,"height":400,"sizes":{"thumbnail":"https://www.gattefosse.com/wordpress/wp-content/uploads/2018/04/EnergiNius-150x150.jpg","thumbnail-width":150,"thumbnail-height":150,"medium":"https://www.gattefosse.com/wordpress/wp-content/uploads/2018/04/EnergiNius-300x105.jpg","medium-width":300,"medium-height":105,"medium_large":"https://www.gattefosse.com/wordpress/wp-content/uploads/2018/04/EnergiNius-768x269.jpg","medium_large-width":474,"medium_large-height":166,"large":"https://www.gattefosse.com/wordpress/wp-content/uploads/2018/04/EnergiNius-1024x358.jpg","large-width":474,"large-height":166,"post-thumbnail":"https://www.gattefosse.com/wordpress/wp-content/uploads/2018/04/EnergiNius-672x372.jpg","post-thumbnail-width":672,"post-thumbnail-height":372,"twentyfourteen-full-width":"https://www.gattefosse.com/wordpress/wp-content/uploads/2018/04/EnergiNius-1038x400.jpg","twentyfourteen-full-width-width":1038,"twentyfourteen-full-width-height":400}},"image_product_finder":{"id":9011,"alt":"EnergiNius","title":"","caption":"","description":"","mime_type":"image/jpeg","url":"https://www.gattefosse.com/wordpress/wp-content/uploads/2018/04/iStock-617394368_vignette.jpg","width":244,"height":163,"sizes":{"thumbnail":"https://www.gattefosse.com/wordpress/wp-content/uploads/2018/04/iStock-617394368_vignette-150x150.jpg","thumbnail-width":150,"thumbnail-height":150,"medium":"https://www.gattefosse.com/wordpress/wp-content/uploads/2018/04/iStock-617394368_vignette.jpg","medium-width":244,"medium-height":163,"medium_large":"https://www.gattefosse.com/wordpress/wp-content/uploads/2018/04/iStock-617394368_vignette.jpg","medium_large-width":244,"medium_large-height":163,"large":"https://www.gattefosse.com/wordpress/wp-content/uploads/2018/04/iStock-617394368_vignette.jpg","large-width":244,"large-height":163,"post-thumbnail":"https://www.gattefosse.com/wordpress/wp-content/uploads/2018/04/iStock-617394368_vignette.jpg","post-thumbnail-width":244,"post-thumbnail-height":163,"twentyfourteen-full-width":"https://www.gattefosse.com/wordpress/wp-content/uploads/2018/04/iStock-617394368_vignette.jpg","twentyfourteen-full-width-width":244,"twentyfourteen-full-width-height":163}},"title":"EnergiNius®","tagline":"Recharge the skin's battery","description_product_finder":"","introduction":"
EnergiNius® protects skin cells from screen-emitted artificial visible light, an added environmental stress induced by a modern lifestyle. Strongly reinforced, the skin is visibly revived and the signs of fatigue disappear in favor of a healthy glow.
Derived from Indian Ginseng (Withania somnifera) roots, EnergiNius® is organic certified and obtained using the innovative NaDES technology. Sourced in Oregon, USA, Withania somnifera is an emblematic plant of Ayurvedic medicine and has been used in traditional medicine for millennia. EnergiNius® contains amino acids and withanolids; the synergetic action of these two phytochemical families supports its high level of efficacy.
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Watch the video to get a comprehensive overview of EnergiNius®: \n
For the first time, the screen emitted artifical visible light (AVL) has been precisely characterized and Gattefossé has developed unique equipment accurately recreating the light emitted by screens.
A nonionic oil-in-water emulsifier for topical formulations that provides high stability in topical fluid lotions and light emulsions over a wide pH range.
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Mixture of PEG-6 stearate and PEG-32 stearate
\n"},{"keys":"EP Name","value":"
Pending
\n"},{"keys":"UNII Code (FDA)","value":"
8LQC57C6B0 33GX5WQC0M
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PEG-6 STEARATE PEG-32 STEARATE
\n"},{"keys":"Handbook of Pharmaceutical Excipients","value":"
Polyoxylethylene stearates
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Consists of a mixture of PEG-6 (MW 300) esters of stearic (C18) acid and PEG-32 (MW 1500) esters of stearic (C18) acid
Polyvalent emulsifier compatible with all types of oils and ideal for topical lotions. Stabilizes and improves sensorial and texture properties. Safety of use is inferred by precedence of use in approved pharmaceutical products.
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and conditions"},"content":{"rendered":"","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_yoast_wpseo_title":"","_yoast_wpseo_metadesc":""},"categories":[48],"tags":[],"acf":{"component":"PageGenericContentCorporate","oneLoad":false,"title":"Terms and conditions","content":"
General Terms and Conditions of Use for the gattefosse.com website :
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Purpose
\n\n
These General Terms and Conditions of Use (“General Terms and Conditions of Use”) apply to the browsing of the website www.gattefosse.com (the “Website”) and the use of its features.
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By accessing the Website, the user (the “User”) acknowledges having read and accepted without reservation all the General Terms and Conditions of Use herein and undertakes to comply with them.
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These General Terms and Conditions of Use may be revised by Gattefossé at any time without any formality other than the online publication of a new amended version, the latter prevailing over any previous version.
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Access to the Website
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The Website is accessible free of charge in any place to any User with internet access.
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Any costs involved in accessing the Website (computer hardware, software, internet connection, etc.) are borne by the User.
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In the event of maintenance work, an event beyond the control of Gattefossé, an outage or in the event of force majeure, access to the Website may be interrupted or suspended without notice or justification and without Gattefossé being held liable.
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In addition, Gattefossé reserves the right to interrupt or definitively cease publication of the Website, at any time, without notice or justification and without being held liable.
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Members’ Section
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Any User who wishes to access the members’ section of the Website (the “Members’ Section”) must register by filling in the form.
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When registering in the Members’ Section, the User undertakes to provide accurate information concerning their civil status, contact details (email address), the company for which they work, their field of activity and the position they hold there,
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Registration is subject to validation by Gattefossé, who are free to refuse a User’s registration, without justification and without being held liable.
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Access to the Members’ Section is controlled by entering the email address provided upon registration and the password selected by the User.
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These identifiers are strictly personal and must not be conveyed to third parties. In all events, the User remains responsible for the use made of them.
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Without prejudice to its other rights and remedies, Gattefossé reserves the right to suspend or delete, without notice, the account of any User who does not comply with these General Terms and Conditions of Use.
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The User may request that their account be deleted by sending an email to: contact@gattefosse.com specifying their first and last names, email address and the reason for their request. Account deletion will be effective within a reasonable timeframe.
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Any deletion of an account, for any reason whatsoever, shall result in the definitive deletion of all the User’s personal information.
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Intellectual Property
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The registered or unregistered trademarks, logos and signs represented on the Website as well as all its content (texts, icons, photographs, illustrations, layouts, etc.), including the content of the Members’ Section, are protected by the French Intellectual Property Code and more specifically by copyright.
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Any reproduction, representation, publication, redistribution or copying of all or part of these elements is subject to the express prior authorisation of Gattefossé and/or the holders of the rights for these elements.
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Non-compliance with this obligation may constitute an act of infringement punishable under Articles L335-2 et seq. of the French Intellectual Property Code.
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Access to the Website shall not be interpreted as conferring on the User any licence or intellectual property right whatsoever over the Website and/or its content other than that of viewing and browsing the Website.
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All Users are also prohibited from using a robot or any other automatic process that enables them to access, vacuum or extract the data contained or presented on the Website.
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Without prejudice to the above, any User duly registered in the Members’ Section may download the media made available in the members’ section. These media may only be used for personal and informational purposes, to the exclusion of any commercial and/or advertising use. The User shall also refrain from (i) deleting or modifying the copyright notices and any other proprietary notices affixed or contained in these media (ii) modifying or altering these media and their content (iii) publishing and distributing, in any manner whatsoever, for consideration or free of charge, these media and their content. More generally, the User shall refrain from directly, indirectly or through third parties, in any way whatsoever, infringing the rights of Gattefossé and/or the rights of third parties on these media.
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Personal data
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Gattefossé may collect and process personal data that Users provide during their browsing of the Website.
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Gattefossé undertakes to collect and process this data in accordance with applicable law and the provisions of its Personal Data Protection Policy.
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Cookies
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When browsing the Website, cookies may be placed on the User’s device (computer, tablet, smartphone). A cookie is a small computer file deposited on the User’s device through their internet browser that allows certain data to be stored in order to facilitate browsing on a website and enable certain functionalities.
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Gattefossé’s use of these cookies is governed by the provisions of its Personal Data Protection Policy.
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Liability
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Gattefossé does not provide any warranty, whether express or implied, concerning the Website and/or all or part of its content.
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Gattefossé will make every effort to ensure that the information presented on the Website is accurate, up-to-date and reliable, but will not be held responsible for any error or omission in this respect.
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The information presented on the Website is provided for information purposes only.
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Consequently, Gattefossé may not be held liable for any damage, direct or indirect, of any kind whatsoever, resulting from the use by the User of the information presented on the Website.
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Gattefossé declines all responsibility for any viruses that may infect the User’s computer hardware due to access to, or use of, the Website.
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Gattefossé cannot be held liable for any difficulties in accessing the Website and/or disruptions to Internet connections. Similarly, the liability of Gattefossé is excluded in the event of force majeure.
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In general, Gattefossé declines all liability in the event of direct or indirect damage, regardless of the causes, origins, nature or consequences that would result from access to and/or use of the Website and/or its content, the User taking sole responsibility for the resulting risks.
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Links to other websites
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The Website may have hypertext links directing the User to other websites. Gattefossé declines all responsibility regarding access to and use of these websites and/or their content, the User alone assuming full responsibility and the resulting risks.
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Applicable law, competent courts
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These General Terms and Conditions of Use are governed by French law. In the event of a dispute, the courts of Lyon shall have sole jurisdiction, including in the event of summary proceedings, third-party claims or multiple defendants.
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General Terms & Conditions of Sale :
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Please find below the General Terms & Conditions of Sale (“T&C’s”) applicable to all sales of products and/or services by the corresponding affiliate of the Gattefossé Group:
Hard fat pessary base with emulsifier to improve dispersibility and wettability of hydrophobic APIs.
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Mixture of hard fat and ethoxylated fatty alcohols
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Mixture of hard fat and ethoxylated fatty alcohols
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8334LX7S21 YRC528SWUY
\n"},{"keys":"Preferred Substance Name (FDA)","value":"
Hard fat Polyoxyl 20 cetostearyl ether
\n"},{"keys":"Handbook of Pharmaceutical Excipientsitory bases, hard fat","value":"
/
\n"},{"keys":"Chemical description","value":"
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Understanding The Role Of In Vitro And In Vivo Evaluation Techniques In Determining the Performance of Lipid-Based Formulations
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Elise Dauphin-Chanard ; Jean-Marie Girard ; Carole Deleglise ; Philippe Caisse
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Fiona Mc Cartney ; David Brayden
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Selecting efficient pharmaceutical binder for developing robust extended release matrices of Compritol ® 888ATO prepared using wet granulation technique
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Part 1 Studying impact on granule & tablet properties
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Part 2 Studying impact on dissolution profiles of ER tablets of different API’s
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K. Deshmukh, A. Shrivastava, S. Banerjee, R. Tiwari, S. Bambarkar, N. Farah
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This study evaluates the binding efficiency of four commonly used pharmaceutical binders to hold hydrophilic API’s of different solubilities with hydrophobic, waxy ER matrices of Compritol ® 888 ATO as sustained release agent by studying their impact on the granule and tablet properties formulated using the same.
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K. Deshmukh, A. Shrivastava, S. Banerjee, R. Tiwari, S. Bambarkar, N. Farah
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