Trouvez l’inspiration avec les dernières formulations développées par notre laboratoire d’applications.
An optimized LBF enables solubilization of the entire therapeutic dose and maintains the drug in solubilized state throughout the digestion process.
\nTo speed up LBF development, we have produced tools to guide you at each stage of development:
\n1 – methods for saturation solubility screening
\n2 – database of solubility of drugs in common pharmaceutical excipients
\n3 – methods for miscibility and dispersability testing
\n4 – miscibility table
\n5 – in vitro lipolysis procedure
\n6 – guideline for preclinical studies
\nDay after day, skin and hair face stress, pollution, UV, and other harsh elements. This constant assault leads to dryness, dullness, and loss of radiance. Additionally, the damage to skin cells can lead to a loss of energy and efficiency. An effective way to restore radiance and energy is to bring more oxygen to cells and thereby boost their metabolism. By increasing their energetic potential, Phylderm® Vegetal stimulates cell renewal, amplifying skin radiance and making hair more resistant to environmental damage.
\n","use_level":"5-10%","naturalite":"","inci":"Hydrolyzed Soy Protein","origin":"Soy is one of the richest sources of vegetable protein. As the starting point of the soy life cycle, soybeans contain all components necessary for the synthesis of major skin proteins.
\nPhylderm® Vegetal is extracted from GMO-free soybeans using a gentle extraction process that guarantees the presence of important peptides in the final product.
\nIn vitro tests prove Phylderm® Vegetal C effectively
\nJuergen Siepmann, Amina Faham, Sophie-Dorothée Clas, Ben J. Boyd, Vincent Jannin, Andreas Bernkop-Schnürch, Hang Zhao, Sébastien Lecommandoux, James C.Evans, Christine Allen, Olivia M. Merkel, Gabriella Costabile, Morgan R. Alexander, Ricky D.Wildman, Clive J.Roberts, Jean-Christophe Leroux
\nInternational Journal of Pharmaceutics, Volume 558, 10 March 2019, Pages 128-142
\nThis article reviews the uses of lipids and polymers in pharmaceutical applications, alone or in combination, with a main focus on oral administration.
\nThese topics were discussed at the Journées galéniques de Saint-Rémy de Provence in 2018, the Scientific Meeting sponsored by Gattefossé Foundation.
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The locavore movement primarily appeared in the USA West Coast with consumers giving the priority to food farmed closed to their home. It progressively expanded to the beauty industry, benefitting to both brands and consumers. The cosmetic industry finds in the locavore movement the opportunity to highlight forgotten local ingredients and to inject dynamism into regional economies. Consumers find in this “local spirit” a resonance with their value and a kind of reassurance.
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(1) Lightspeed/Mintel 2017, 1000 internet users aged 16+ per country
\n (2) https://www.happi.com/issues/2023-01-01/view_features/up-coming-indie-personal-care-brands-for-2023/
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\nIn this study the authors developed stable anhydrous and hydrous creams containing 40% Transcutol® HP, using predictive techniques to select appropriate excipients.
\n\nMasumi Dave, M.S., Jason Le Pree, Ph.D., R.Ph. – Gattefossé USA
\nIn this study the authors showed that Thermal Activity Monitoring is a useful technique to detect at early stage potential interaction between API and excipients, using less time and resources than conventional techniques.
\nTAM technique is used routinely in Gattefossé North American Technical Center of Excellence to speed up formulation development.
\n\nGelucire 48/16®: A Versatile Non-Ionic Solid Solubilizer for Tablets of Poorly Water-Soluble Drugs
\n Agnivesh Shrivastava, Ketkee Deshmukh, Nabil Farah, Sharda Gurram, Sunil Bambarkar
A solid dispersion of ticagrelor and Gelucire® 48/16 is prepared to increase drug solubility. The solid dispersion is converted into tablets. The formulated tablets showed improved dissolution rate compared to the market reference.
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\nDans cette section, vous trouverez les derniers communiqués de presse, les photos et les vidéos publiés par Gattefossé et sa Fondation d’entreprise.
\nVous avez des questions ? N’hésitez pas à nous contacter pour tout complément d’information. | \nClaudine Blondet press@gattefosse.com | \n
\n
\n\n
\n
Gattefossé développe et produit des ingrédients de spécialité pour les industries cosmétique et pharmaceutique. Spécialiste de la chimie des lipides et de l’extraction végétale, Gattefossé propose également son expertise en formulation approfondie dans ses laboratoires d’applications.
\nGattefossé commercialise ses produits dans plus de 60 pays grâce à ses 12 filiales et son réseau de distribution qui assurent un support technique et marketing solide à ses clients : 75% de ses ventes sont réalisées à l’export.
\nInnovation, qualité, stabilité et éthique sont les valeurs clés de l’entreprise depuis sa création.
\nGattefossé a été fondée à Lyon, France, en 1880 par M. Louis Gattefossé. Depuis sa création, l’entreprise est indépendante et gouvernée par les familles fondatrices et elle emploie plus de 300 personnes dans le monde.
\n\n\n\n
\n
Cliquez sur les photos pour télécharger les portraits HD de notre Président, Jacques Moyrand et de notre Directeur Général, Eduardo De Purgly.
\nCopyright Véronique Védrenne
\n\n\n
15 avril 2019 – Gattefossé obtient le statut OR sur EcoVadis
\n
19 février 2019 – Gattefossé lance son nouvel émulsionnant E/H à in-cosmetics global
\n
17 décembre 2018 – COSMET’AGORA 2019, nouvelle édition de l’outil Gattefossé INSPIRATION
\n
16 octobre 2018 – Aromathérapie : la Fondation Gattefossé
\n soutient trois établissements
\n\n
\n
10 juillet 2018 – Gattefossé renouvelle sa certification ISO 9001 et passe à la version 2015
\n
5 juin 2018 – Lancement officiel du Label ERI 360°
\n
9 mai 2018 – Gattefossé et Ambiotis ont exploré les mécanismes de la résolution de l’inflammation au cours du vieillissement cutané
\n
10 avril 2018 – Rencontrez les #GénérationsConnectées à in-cosmetics global 2018
\n
29 mars 2018 – EnergiNius™ : Gattefossé lance un nouvel actif à in-cosmetics Amsterdam 2018
20 février 2018 – Gattefossé Asie Pacifique obtient la certification ISO9001 version 2015
\n\n
\n
3 janvier 2018 – COSMETAGORA 2018, Gattefossé se lance un nouveau challenge
\n\n\n\n\n\n
\n\n
20 septembre 2017 – Aromathérapie : La Fondation Gattefossé soutient deux établissements
\n\n\n
26 avril 2017- Gattefossé annonce l’inauguration de son Centre Technique d’Excellence en Amérique du Nord
Contactez nous pour recevoir le Dossier de Presse
\n\n
29 mars 2017 – Gattefossé à in-cosmetics Global : Show true emotions
\n\n\n
\n
6 mars 2017 – Gattefossé obtient la certification Mass Balance RSPO
\n
8 février 2017 – Nouveau lancement : Gatuline® Link n Lift – Redesign the eye contour
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A glyceride with an intermediate melting point containing PEG-8 esters. A powder wetting agent and lubricant for effervescent and fast-dissolving tablets.
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\nSolubilisation behaviour of poorly water-soluble drugs during digestion of solid SMEDDS
\nLipid-based nanosuspensions for oral delivery of peptides, a critical review
\nSelf-emulsifying peptide drug delivery systems: How to make them highly mucus permeating
\nCompritol® 888 ATO: a sustained release lipid matrix for once a day aceclofenac tablets
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Interest of carriers for the development of solid self-emulsifying drug delivery systems
\nBibliography on Gattefossé’s products. 2004-2005 review.
\nSolubilisation behaviour of poorly water-soluble drugs during digestion of solid SMEDDS
\nLipid-based nanosuspensions for oral delivery of peptides, a critical review
\nSelf-emulsifying peptide drug delivery systems: How to make them highly mucus permeating
\nCompritol® 888 ATO: a sustained release lipid matrix for once a day aceclofenac tablets
\nInterest of carriers for the development of solid self-emulsifying drug delivery systems
\nBibliography on Gattefossé’s products. 2004-2005 review.
\nDevelopment of immediate release pellets of poorly soluble compounds using Gelucire® 44/14
\nYvonne Rosiaux, Amandine Forest, Jean-Michel Girard, Carole Deleglise, Liz Sheehan and Delphine Marchaud
\n Journal of Drug Delivery Science and Technology 48 (2018) 437–449
In this study the authors used:
\n – A design of experiment, to evaluate the effect of process parameters (blending speed, chopper speed and coating time) on drug particle size.
\n – Potassium chloride as model drug.
The study showed:
\n – Individual particle coating was achieved at 450 rpm with 20% glyceryl distearate (Precirol® ATO 5) at 48°C
\n – High shear coating is as efficient as fluid bed coating for taste masking
\n – A trained sensory panel confirmed the effectiveness of the process on taste masking
C Morin and Y Rosiaux
\nRosiaux Y., Forest A., Girard J.M., Deleglise C., Marchaud D.
\nAAPS 2017
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