Skin Biology
Gattefossé opened a cell biology laboratory, including clean rooms, at its headquarters in 2013. Laboratory staff culture skin cells and tissues and carry out research in skin biology aimed at developing cosmetic substantiation tests and innovative investigative models.
Cell culture models to substantiate cosmetic active ingredients
Our active ingredients are substantiated through a battery of efficacy tests adapted to molecular screening:
- Simple models of monolayer cell culture (fibroblasts, keratinocytes, melanocytes, adipocytes, and sebocytes) are used to investigate the efficacy of active ingredients on cell metabolism (cell proliferation and protein synthesis),
- Pluristratified models, such as spheroid cultures, are developed to reach matrix targets and complete the screening process.
3D models of artificial skin
We also work with advanced 3D artificial skin models and reconstructed epidermis, dermis, and skin. Human skin biopsies are used to mimic skin physiology and isolate innovative biological mechanisms and targets. These cultures effectively elucidate the mechanisms of action and biological properties of our active ingredients.
Innovation through research in skin biology
Follow the guide
Gattefossé invites you behind the scene to discover its skin biology laboratory from the inside. A virtual tour at 360° to dive into the fascinating universe of cell culture.
