A nonionic water-insoluble surfactant used as cosurfactant in oral lipid-based formulation SEDDS and SMEDDS. Cosurfactant and solubilizer in topical dosage forms.
Propylene glycol monocaprylate (type II)
PROPYLENE GLYCOL CAPRYLATE
Consists of propylene glycol esters of caprylic acid (C8), mainly composed of monoesters and a small fraction of diesters.
Solubilizer for poorly-soluble APIs and bioavailability enhancer. Cosurfactant in LFCS Type II (SEDDS) and Type III (SMEDDS) formulations. Solubilizer and cosurfactant for microemulsion in topical formulation. Safety of use is inferred by precedence of use in approved pharmaceutical products.
Self-emulsifying lipid formulation for oral applications. Topical emulgel, microemulsion.