Dermasol: excipients for efficient skin penetration

Discover Dermasol and learn how to formulate topical dosage forms for efficient skin penetration.

 

 

Three main steps govern drug diffusion from the formulation to the skin:

  • Solubility: the formulation must solubilize a sufficient amount of drug to reach the effective concentration at the target site
  • Partition: the drug must partition out of the delivery vehicle into the upper layers of the SC
  • Diffusion: the drug molecule diffuses through the SC mainly via the intercellular path

Discover Gattefossé range of excipients for skin penetration