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Caprylocaproyl macrogol-8 glycerides EP
Caprylocaproyl polyoxyl-8 glycerides NF

Other names

Caprylocaproyl polyoxylglycerides
PEG-8 Caprylic/Capric Glycerides (FDA IIG)

Key Features

•A non-ionic water dispersible surfactant composed of well-characterised polyethylene glycol (PEG) esters, a small glyceride fraction and free PEG.


•Able to self-emulsify on contact with aqueous media forming a fine dispersion ie. microemulsion (SMEDDS).

•Solubilizer and wetting agent: Surfactive power improves the solubility and wettability of active pharmaceutical ingredients in vitro and in vivo.



•An oil-in-water surfactant used to solubilize active pharmaceutical ingredients and promote drug penetration and permeation.

Safety of use is supported by extensive toxicological evaluations and precedence of use in approved pharmaceutical products.

Physical Form

  • liquid

Hydrophilic-Lipophilic Balance (HLB)

  • 12

Field of use

  • •Human pharmaceutical products, veterinary products excluding food producing animals

Administration Route

  • Oral

Formulation techniques and dosage forms

•Suitable for hard gelatin and soft gelatin capsules.
•Suitable for adsorption onto neutral carrier powders for use in tablets, capsule filling and sachets.
•Use in topical ointments, microemulsions, emulsions and gels.
•Use in transdermal patches.